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Ldb1 and Rnf12-dependent regulation of Lhx2 controls the relative balance between neurogenesis and gliogenesis in retina 
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Electroporation of Lhx2 promotes the formation of wfACs. (a-c) Morphology of a wfAC generated following electroporation of Lhx2 . (d) Generated wide field amacrine cells co-express the pan-amacrine marker PAX6. (e-m) Co-labeling with amacrine cell subtype selective markers reveals that amacrine cells generated by Lhx2 electroporation do not fall within any well-established molecular category. ISLET 1, CHAT-cholinergic starburst amacrine cells; GABA, <t>GAD2-GABAergic</t> amacrine cells; GLYCINE-glycinergic amacrine cells; VGLUT3-glutamatergic amacrine cells; CALB2-mixed population primarily AII amacrine cells, A19 amacrine cells, and non-AII glycine immunoreactive amacrine cells; TH-dopaminergic wide field amacrine cells; DAB1-AII amacrine cells. GCL, ganglion cell layer; INL, inner nuclear layer; outer nuclear layer; s inner plexiform layer sublamina. Scale bars, 50 ¼m (all panels).
Ldb1 and Rnf12-dependent regulation of Lhx2 controls the relative balance between neurogenesis and gliogenesis in retina bioRxiv, 2017 Sep 04
"Electroporation of Lhx2 promotes the formation of wfACs. (a-c) Morphology of a wfAC generated following electroporation of Lhx2 . (d) Generated wide field amacrine cells co-express the pan-amacrine marker PAX6. (e-m) Co-labeling with amacrine cell subtype selective markers reveals that amacrine cells generated by Lhx2 electroporation do not fall within any well-established molecular category. ISLET 1, CHAT-cholinergic starburst amacrine cells; GABA, <t>GAD2-GABAergic</t> amacrine cells; GLYCINE-glycinergic amacrine cells; VGLUT3-glutamatergic amacrine cells; CALB2-mixed population primarily AII amacrine cells, A19 amacrine cells, and non-AII glycine immunoreactive amacrine cells; TH-dopaminergic wide field amacrine cells; DAB1-AII amacrine cells. GCL, ganglion cell layer; INL, inner nuclear layer; outer nuclear layer; s inner plexiform layer sublamina. Scale bars, 50 ¼m (all panels). "
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